Job Details
Postdoctoral Researcher for Cornea Chip
Postdoctoral Researcher for Cornea Chip
Job Summary
The Kim Laboratory at the University of Utah (Department of Mechanical Engineering and John A. Moran Eye Center) is seeking a highly motivated, creative, and collaborative Postdoctoral Research Fellow. The fellow will lead the biological arm of an NIH-funded project on corneal mechanotransduction in keratoconus. This project sits at the intersection of corneal biology, mechanobiology, and organ-on-chip engineering, and builds on the laboratory's recent work on curvature-dependent regulation of corneal stromal cells (Nature Communications, 2025).
The successful candidate will generate and validate CRISPR/Cas9 knockout corneal stromal cell lines. They will also study how curvature and mechanical load regulate corneal cell behavior in hydraulically controlled organ-chip platforms, and identify the mechanotransduction pathways underlying keratoconus progression. Candidates should hold a Ph.D. in Cell Biology, Molecular Biology, Vision Science, Biomedical Engineering, or a related field, with a strong track record of first-author publications.
This role requires hands-on expertise in mammalian cell culture, CRISPR/Cas9 genome editing, and core molecular and imaging techniques such as qPCR, Western blotting, immunocytochemistry, and confocal microscopy. A solid understanding of mechanotransduction signaling, including YAP/TAZ, cytoskeletal remodeling, and ECM regulation, is essential. The preferred candidate will also bring experience with corneal or ocular cell culture, 3D or microfluidic culture systems, and RNA-seq or quantitative image analysis.
Responsibilities
Minimum Qualifications
Preferences
Special Instructions
Requisition Number: PRN46629B
Full Time or Part Time? Full Time
Work Schedule Summary: Monday -- Friday 9am -- 5pm
Department: 00068 - Mechanical Engineering
Location: Campus
Pay Rate Range: 65,000-70,000
Close Date: 12/31/2026
Open Until Filled:
To apply, visit https://utah.peopleadmin.com/postings/211581
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